You should use either indexing or the subset function. For example :

R> df <- data.frame(x=1:5, y=2:6, z=3:7, u=4:8)
R> df
  x y z u
1 1 2 3 4
2 2 3 4 5
3 3 4 5 6
4 4 5 6 7
5 5 6 7 8

Then you can use the which function and the - operator in column indexation :

R> df[ , -which(names(df) %in% c("z","u"))]
  x y
1 1 2
2 2 3
3 3 4
4 4 5
5 5 6

Or, much simpler, use the select argument of the subset function : you can then use the - operator directly on a vector of column names, and you can even omit the quotes around the names !

R> subset(df, select=-c(z,u))
  x y
1 1 2
2 2 3
3 3 4
4 4 5
5 5 6

Note that you can also select the columns you want instead of dropping the others :

R> df[ , c("x","y")]
  x y
1 1 2
2 2 3
3 3 4
4 4 5
5 5 6

R> subset(df, select=c(x,y))
  x y
1 1 2
2 2 3
3 3 4
4 4 5
5 5 6

===============================

Simple R functions to keep or remove data frame columns

This function removes columns from a data frame by name:

removeCols <- function(data, cols){ return(data[,!names(data) %in% cols]) }

This function keeps columns of a data frame by name:

keepCols <- function(data, cols){
return(data[,names(data) %in% cols]) }

or just one function

colKeepRemove <- function(data, cols, remove=1){
if(remove == 1){ return(data[,!names(data) %in% cols]) }
else { return(data[,!names(data) %in% cols]) }}

===============================

data(mtcars)

mtcars[mtcars[, "mpg"]>25, ]

                mpg cyl  disp  hp drat    wt  qsec vs am gear carb
Fiat 128       32.4   4  78.7  66 4.08 2.200 19.47  1  1    4    1
Honda Civic    30.4   4  75.7  52 4.93 1.615 18.52  1  1    4    2
Toyota Corolla 33.9   4  71.1  65 4.22 1.835 19.90  1  1    4    1
Fiat X1-9      27.3   4  79.0  66 4.08 1.935 18.90  1  1    4    1
Porsche 914-2  26.0   4 120.3  91 4.43 2.140 16.70  0  1    5    2
Lotus Europa   30.4   4  95.1 113 3.77 1.513 16.90  1  1    5    2


mtcars[mtcars$mpg>25, ]

                mpg cyl  disp  hp drat    wt  qsec vs am gear carb
Fiat 128       32.4   4  78.7  66 4.08 2.200 19.47  1  1    4    1
Honda Civic    30.4   4  75.7  52 4.93 1.615 18.52  1  1    4    2
Toyota Corolla 33.9   4  71.1  65 4.22 1.835 19.90  1  1    4    1
Fiat X1-9      27.3   4  79.0  66 4.08 1.935 18.90  1  1    4    1
Porsche 914-2  26.0   4 120.3  91 4.43 2.140 16.70  0  1    5    2
Lotus Europa   30.4   4  95.1 113 3.77 1.513 16.90  1  1    5    2

subset(mtcars, mpg>25)

                mpg cyl  disp  hp drat    wt  qsec vs am gear carb
Fiat 128       32.4   4  78.7  66 4.08 2.200 19.47  1  1    4    1
Honda Civic    30.4   4  75.7  52 4.93 1.615 18.52  1  1    4    2
Toyota Corolla 33.9   4  71.1  65 4.22 1.835 19.90  1  1    4    1
Fiat X1-9      27.3   4  79.0  66 4.08 1.935 18.90  1  1    4    1
Porsche 914-2  26.0   4 120.3  91 4.43 2.140 16.70  0  1    5    2
Lotus Europa   30.4   4  95.1 113 3.77 1.513 16.90  1  1    5    2




===============================
REF:
http://stackoverflow.com/questions/4605206/drop-columns-r-data-frame
http://stackoverflow.com/questions/5234117/how-to-drop-columns-by-name-in-a-data-frame
http://ewens.caltech.edu/2011/05/17/simple-r-functions-to-keep-or-remove-data-frame-columns/

keep or remove data frame columns in R

Simple R functions to keep or remove data frame columns