web.config add handlers and httpmodule to System.Web section.

<?xml version="1.0" encoding="utf-8"?>
<!--
  For more information on how to configure your ASP.NET application, please visit
  http://go.microsoft.com/fwlink/?LinkId=152368
  -->

<configuration>
  <appSettings>
    <add key="webpages:Version" value="2.0.0.0" />
    <add key="PreserveLoginUrl" value="true" />
    <add key="ClientValidationEnabled" value="true" /> 
    <add key="UnobtrusiveJavaScriptEnabled" value="true" /> 
  </appSettings>
    
  <system.web>
    <compilation debug="true" targetFramework="4.0">
      <assemblies>
        <add assembly="System.Web.Abstractions, Version=4.0.0.0, Culture=neutral, PublicKeyToken=31BF3856AD364E35" />
        <add assembly="System.Web.Helpers, Version=2.0.0.0, Culture=neutral, PublicKeyToken=31BF3856AD364E35" />
        <add assembly="System.Web.Routing, Version=4.0.0.0, Culture=neutral, PublicKeyToken=31BF3856AD364E35" />
        <add assembly="System.Web.Mvc, Version=4.0.0.0, Culture=neutral, PublicKeyToken=31BF3856AD364E35" />
        <add assembly="System.Web.WebPages, Version=2.0.0.0, Culture=neutral, PublicKeyToken=31BF3856AD364E35" />
      </assemblies>
    </compilation>
    <!--IIS6 httpModules-->
    <httpModules>
      <add name="HttpModuleService" type="as.Core.Module.HttpModuleService, as.Core.Module" />
    </httpModules>
    <httpHandlers>
        <add verb="*" path="*.axd" type="as.Core.Upload.ThumbnailHandler, as.Core.Upload" />
    </httpHandlers>
    <authentication mode="Forms">
      <forms loginUrl="~/Account/LogOn" timeout="2880" />
    </authentication>

    <pages>
      <namespaces>
        <add namespace="System.Web.Helpers" /> 
        <add namespace="System.Web.Mvc" />
        <add namespace="System.Web.Mvc.Ajax" />
        <add namespace="System.Web.Mvc.Html" />
        <add namespace="System.Web.Routing" />
        <add namespace="System.Web.WebPages" />
      </namespaces>
    </pages>

    <globalization requestEncoding="utf-8" responseEncoding="utf-8" />
    <httpRuntime requestValidationMode="2.0" />
  </system.web>
  <system.webServer>
    <validation validateIntegratedModeConfiguration="false" />
    <!--IIS7 httpModules-->
    <!--<modules runAllManagedModulesForAllRequests="true">
      <add name="HttpModuleService" type="as.Core.Module.HttpModuleService, as.Core.Module"/>
    </modules>-->
  </system.webServer>

  <runtime>
    <assemblyBinding xmlns="urn:schemas-microsoft-com:asm.v1">
      <dependentAssembly>
        <assemblyIdentity name="System.Web.Mvc" publicKeyToken="31bf3856ad364e35" />
        <bindingRedirect oldVersion="0.0.0.0-4.0.0.0" newVersion="4.0.0.0" />
      </dependentAssembly>
    </assemblyBinding>
  </runtime>
</configuration>