As an ophthalmologist, David Ingvoldstad sees much more about his patients' health than just their eyes. Thanks to the clues the eyes provide, he regularly alerts patients to possible autoimmune diseases like rheumatoid arthritis and lupus, monitors progression of their diabetes and once even suspected -- correctly, as it turned out -- that a patient had a brain tumor on the basis of the pattern of her vision changes.
ophthalmologist:眼科医生 autoimmune:自身免疫的 rheumatoid:患风湿症的 arthritis:关节炎
lupus:红斑狼疮 diabetes:糖尿病 brain tumor:脑肿瘤,脑瘤
Because the body's systems are interconnected, changes in the eye can reflect those in the vascular, nervous and immune system, among others. And because the eyes are see-through in a way other organs aren't, they offer a unique glimpse into the body. Blood vessels, nerves and tissue can all be viewed directly through the eye with specialized equipment.
interconnected:连通的;有联系的,互相连接 vascular:血管,脉管,导管 immune:免疫的,免除的
see-through:透明的,穿透的 glimpse:瞥见,一看,隐约闪现 tissue:组织,纸巾,薄纱
With regular monitoring, eye doctors can be the first to spot certain medical conditions and can usher patients for further evaluation, potentially leading to earlier diagnosis and treatment. Clots in the tiny blood vessels of the retina can signal a risk for stroke, for example, and thickened blood-vessel walls along with narrowing of the vessels can signal high blood pressure. In some cases, examining the eye can help confirm some of the diagnoses or help differentiate disorders from each other.
usher:引导,接待,迎接,开辟,接待员 diagnosis:诊断,分析 Clot:血块,凝块 retina:视网膜
vessels:血管,船舶,容器 differentiate:区分,区别
'There's no question the eye has always been the window to the body,' says Emily Chew, deputy director of the epidemiology division at the National Eye Institute. She adds, 'Anybody with any visual changes . . . should be seeing someone right away.
deputy:代理人,代表,代理的 epidemiology:流行病学;传染病学
Scientists are working to advance their knowledge of what the eye can reveal about diseases. For instance, researchers are studying how dark spots on the back of the eye known as CHRPE, or congenital hypertrophy of the retinal pigment epithelium, are associated with certain forms of colon cancer, and how dementia-related changes are signaled in the eye, such as how the eye reacts to light. Other scientists, like Dr. Chew, are studying how to keep the eye healthier for longer, which could be good for the health of the eye as well as the rest of the body.
congenital:先天的,天生的,天赋的 hypertrophy:肥大,肥厚,过度增大 colon cancer:结肠癌,直肠癌
retinal pigment epithelium:视网膜色素上皮 dementia:痴呆症,失智症
Companies are building enhanced technology that allow for better viewing of the eye. Scotland-based Optos, for example, created a machine that allows for better screening of the periphery of the retina. The machines can now be found in doctors' offices and research clinics. Instead of the typical 30-degree view of the eye, it offers a 200-degree view. Being able to see more of the periphery could mean earlier or more accurate diagnosis of various diseases and may also be coupled with intervention tools to improve treatment. Optos is currently funding a study of the use of retinal imaging to diagnose heart disease, according to Anne Marie Cairns, head of its clinical development.
periphery: 外围,边缘;圆周;圆柱体表面 clinic:临床,诊所 intervention:介入,调停,妨碍
The eye's job is to deliver vision by converting incoming light information into messages that the brain can understand. But problems in vision can indicate a problem outside of the eye itself.
One critical structure in the eye is the retina, which allows us to experience vision. It is made of brain tissue and contains many blood vessels. Changes in vessels in other parts of the body are reflected in the retina as well, sometimes more noticeably or sooner than elsewhere in the body.
The eyes can help predict stroke risk, particularly important to people with heart disease and other stroke risk factors. That is because blood clots in the arteries of the neck and head that might lead to stroke are often visible as retinal emboli, or clots, in the tiny blood vessels of the eye, according to the National Eye Institute.
artery:动脉,干道,主流 emboli:栓子,活塞(embolus的复数)
The immune system's interaction with the eyes can be telling, too, yielding information about autoimmune diseases or infections in the rest of the body. Sometimes eye symptoms may appear before others, like joint pain, in patients.
symptoms:症状,病症 joint pain:关节酸痛
For instance, inflammation in the optic nerve can signal problems in an otherwise healthy, young person. Along with decreased vision and sometimes pain, it can suggest multiple sclerosis. If the optic disc, a portion of the optic nerve, is swollen, and the patient has symmetrical decreased field of vision, such as a decreased right visual field in both eyes, they may need an evaluation for a brain tumor -- a rare circumstance.
inflammation:炎症,发炎,发火 optic nerve:视觉神经 sclerosis:硬化症,细胞壁硬化 optic disc:视神经盘
swollen: 肿胀的,浮肿的;浮夸的;激动兴奋的 symmetrical:均匀的,对称的
If immune cells like white blood cells are seen floating in the vitreous of the eye, it could signal a local eye infection or one that is spread throughout the body.
vitreous:玻璃体,玻璃状的,晶状体
Diabetes is one disease that can cause major changes in the eye. In diabetic retinopathy, a common cause of blindness, blood vessels hemorrhage and leak blood and fluid. When blood vessels don't function properly, they can potentially cause eye tissue to be deprived of oxygen and to die, leaving permanent vision damage.
retinopathy:视网膜病 hemorrhage:出血 deprived of:缺乏,剥夺
Also, in diabetic patients additional blood vessels may grow in the eye, anchoring themselves into the sticky gel known as the vitreous, which fills a cavity near the retina. This condition can cause further problems if the retina tears when it tries to separate from the vitreous -- a common occurrence as people age -- but is tangled by growth of new blood vessels.
anchor:抛锚,使固定 gel:凝胶,胶体 cavity:腔,洞,凹处 tangle:纠缠,处于混乱状态,纠纷
Usually diabetic patients who come in for eye exams already know they have the disease, and the primary purpose of an eye exam is to make sure they don't have diabetic retinopathy or, if they did have it, that the condition hasn't progressed, say eye doctors like Dr. Ingvoldstad, a private practitioner at Midwest Eye Care in Omaha, Neb. But once in a while there is a patient who has noticed vision changes but didn't realize he or she had diabetes until alerted during an eye exam that there were signs of the eye disease that is consistent with the condition, he says.
diabetic retinopathy:糖尿病视网膜病变 practitioner:开业者,从业者 consistent with:符合,与....一致
The American Academy of Ophthalmology recommends eye examinations whenever individuals notice any vision changes or injury. Adults with no symptoms or known risk factors for eye disease should get a base line exam by age 40 and return every two to four years for evaluations until their mid-50s. From 55 to 64, the AAO recommends exams every one to three years, and every one to two years for those 65 and older.
Ophthalmology:眼科学