var t = new Timer(TimerCallback);
// Figure how much time until 4:00
DateTime now = DateTime.Now;
DateTime fourOClock = DateTime.Today.AddHours(16.0);
// If it's already past 4:00, wait until 4:00 tomorrow
if (now > fourOClock)
{
fourOClock = fourOClock.AddDays(1.0);
}
int msUntilFour = (int)((fourOClock - now).TotalMilliseconds);
// Set the timer to elapse only once, at 4:00.
t.Change(msUntilFour, Timeout.Infinite);