Python具有强大的扩展能力，以下列出了50个很棒的Python模块，包含几乎所有的需要：比如Databases，GUIs，Images, Sound, OS interaction, Web,以及其他。推荐收藏。
Graphical interface wxPython http://wxpython.org
Graphical interface pyGtk http://www.pygtk.org
Graphical interface pyQT http://www.riverbankcomputing.co.uk/pyqt/
Graphical interface Pmw http://pmw.sourceforge.net/
Graphical interface Tkinter 3000 http://effbot.org/zone/wck.htm
Graphical interface Tix http://tix.sourceforge.net/
Database MySQLdb http://sourceforge.net/projects/mysql-python
Database PyGreSQL http://www.pygresql.org/
Database Gadfly http://gadfly.sourceforge.net/
Database SQLAlchemy http://www.sqlalchemy.org/
Database psycopg http://www.initd.org/pub/software/psycopg/
Database kinterbasdb http://kinterbasdb.sourceforge.net/
Database cx_Oracle http://www.cxtools.net/default.aspx?nav=downloads
Database pySQLite http://initd.org/tracker/pysqlite
MSN Messenger msnlib http://auriga.wearlab.de/~alb/msnlib/
MSN Messenger pymsn http://telepathy.freedesktop.org/wiki/Pymsn
MSN Messenger msnp http://msnp.sourceforge.net/
Network Twisted http://twistedmatrix.com/
Images PIL http://www.pythonware.com/products/pil/
Images gdmodule http://newcenturycomputers.net/projects/gdmodule.html
Images VideoCapture http://videocapture.sourceforge.net/
Sciences and Maths scipy http://www.scipy.org/
Sciences and Maths NumPy http://numpy.scipy.org//
Sciences and Maths numarray http://www.stsci.edu/resources/software_hardware/numarray
Sciences and Maths matplotlib http://matplotlib.sourceforge.net/
Games Pygame http://www.pygame.org/news.html
Games Pyglet http://www.pyglet.org/
Games PySoy http://www.pysoy.org/
Games pyOpenGL http://pyopengl.sourceforge.net/
Jabber jabberpy http://jabberpy.sourceforge.net/
Web scrape http://zesty.ca/python/scrape.html
Web Beautiful Soup http://crummy.com/software/BeautifulSoup
Web pythonweb http://www.pythonweb.org/
Web mechanize http://wwwsearch.sourceforge.net/mechanize/
Localisation geoname.py http://www.zindep.com/blog-zindep/Geoname-python/
Serial port pySerial http://pyserial.sourceforge.net/
Serial port USPP http://ibarona.googlepages.com/uspp
Parallel Port pyParallel http://pyserial.sourceforge.net/pyparallel.html
USB Port pyUSB http://bleyer.org/pyusb/
Windows ctypes http://starship.python.net/crew/theller/ctypes/
Windows pywin32 http://sourceforge.net/projects/pywin32/
Windows pywinauto http://www.openqa.org/pywinauto/
Windows pyrtf http://pyrtf.sourceforge.net/
Windows wmi http://timgolden.me.uk/python/wmi.html
PDA/GSM/Mobiles pymo http://www.awaretek.com/pymo.html
PDA/GSM/Mobiles pyS60 http://sourceforge.net/projects/pys60
Sound pySoundic http://pysonic.sourceforge.net/
Sound pyMedia http://pymedia.org/
Sound FMOD http://www.fmod.org/
Sound pyMIDI http://www.cs.unc.edu/Research/assist/developer.shtml
GMail libgmail http://libgmail.sourceforge.net/
Google pyGoogle http://pygoogle.sourceforge.net/
Expect pyExpect http://pexpect.sourceforge.net/
WordNet pyWordNet http://osteele.com/projects/pywordnet/
Command line cmd http://blog.doughellmann.com/2008/05/pymotw-cmd.html
Compiler backend llvm-py http://mdevan.nfshost.com/llvm-py/
3D VPython http://vpython.org