(pymysql.err.OperationalError) (2003, "Can't connect to MySQL server on 'localhost' ([Errno 61] Connection refused)")

本地数据库能通过root和密码正常登录

逐一排查问题

1，查看端口是否正确（使用的默认端口 3306）

mysql> show global variables like 'port';

结果端口为0

2，修改端口号

查看/Library/LaunchDaemons下的com.oracle.oss.mysql.mysqld.plist发现根本就没有Port相关的配置

于是尝试解决;

2.1，停止MySQL服务

sudo /usr/local/mysql/support-files/mysql.server stop

输入本机密码即可

2.2，在com.oracle.oss.mysql.mysqld.plist文件中的ProgramArguments下添加<string>--port=3306</string>保存退出

<key>ProgramArguments</key>
        <array>
            <string>/usr/local/mysql/bin/mysqld</string>
            <string>--user=_mysql</string>
            <string>--basedir=/usr/local/mysql</string>
            <string>--datadir=/usr/local/mysql/data</string>
            <string>--plugin-dir=/usr/local/mysql/lib/plugin</string>
            <string>--log-error=/usr/local/mysql/data/mysqld.local.err</string>
            <string>--pid-file=/usr/local/mysql/data/mysqld.local.pid</string>
            <string>--keyring-file-data=/usr/local/mysql/keyring/keyring</string>
            <string>--early-plugin-load=keyring_file=keyring_file.so</string>
            <string>--port=3306</string>
        </array>

重启MySQL数据库，再次查看MySQL端口，变为了 3306

重新连接数据库，成功！

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参考：

启动MySQL服务

sudo /usr/local/MySQL/support-files/mysql.server start

停止MySQL服务

sudo /usr/local/mysql/support-files/mysql.server stop

重启MySQL服务

sudo /usr/local/mysql/support-files/mysql.server restart