nginx: [error] invalid PID number "" in "/usr/local/nginx/logs/nginx.pid"

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tty:[0] jobs:[0] cwd:[/opt/nginx/conf]
12:45 [root@a02.cmsapi]$ /usr/local/nginx/sbin/nginx -s reload
nginx: [error] invalid PID number "" in "/usr/local/nginx/logs/nginx.pid"

tty:[0] jobs:[0] cwd:[/opt/nginx/conf]
12:45 [root@a02.cmsapi]$ ps -ef | grep nginx
root       646     1  0 May07 ?        00:00:00 nginx: master process /opt/nginx/sbin/nginx -c /opt/nginx/conf/nginx.conf
www        647   646  0 May07 ?        00:00:00 nginx: worker process                             
www        648   646  0 May07 ?        00:00:01 nginx: worker process                             
www        650   646  0 May07 ?        00:00:00 nginx: worker process                             
www        651   646  0 May07 ?        00:00:01 nginx: worker process                             
www        652   646  0 May07 ?        00:00:00 nginx: worker process                             
www        653   646  0 May07 ?        00:00:01 nginx: worker process                             
www        655   646  0 May07 ?        00:00:01 nginx: worker process                             
www        656   646  0 May07 ?        00:00:00 nginx: worker process                             
root      7712  3274  0 12:45 pts/0    00:00:00 grep nginx
tty:[0] jobs:[0] cwd:[/opt/nginx/conf]
12:45 [root@a02.cmsapi]$ cat /usr/local/nginx/logs/nginx.pid
tty:[0] jobs:[0] cwd:[/opt/nginx/conf]
12:46 [root@a02.cmsapi]$ echo 646 > /usr/local/nginx/logs/nginx.pid
tty:[0] jobs:[0] cwd:[/opt/nginx/conf]
12:47 [root@a02.cmsapi]$ /usr/local/nginx/sbin/nginx -s reload

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