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  • HSCR | Hirschsprung‘s disease | 巨结肠 | 研究进展

    这个网站介绍得很详细:Hirschsprung Disease,基本的定义、病因、诊断。

      

    Hirschsprung disease — integrating basic science and clinical medicine to improve outcomes - 2018年的Nature review,值得好好看,从遗传到发育,再到诊断。但是遗传发育的部分偏少,建立看里面的综述。

    Hirschsprung是人名,也就是第一个发现并定义巨结肠的人。

    Many excellent reviews describe cellular and molecular mechanisms of ENS development17,77–82.

    17. Uesaka, T., Young, H. M., Pachnis, V. & Enomoto, H. Development of the intrinsic and extrinsic innervation of the gut. Dev. Biol. 417, 158–167 (2016).

    77. Heuckeroth, R. O. & Schafer, K. H. Gene-environment interactions and the enteric nervous system: Neural plasticity and Hirschsprung disease prevention. Dev. Biol. 417, 188–197 (2016).

    78. Bondurand, N. & Southard-Smith, E. M. Mouse models of Hirschsprung disease and other developmental disorders of the enteric nervous system: old and new players. Dev. Biol. 417, 139–157 (2016).

    79. Avetisyan, M., Schill, E. M. & Heuckeroth, R. O. Building a second brain in the bowel. J. Clin. Invest. 125, 899–907 (2015). 80. Lake, J. I. & Heuckeroth, R. O. Enteric nervous system development: migration, differentiation, and disease. Am. J. Physiol. Gastrointest. Liver Physiol. 305, G1–G24 (2013).

    80. Lake, J. I. & Heuckeroth, R. O. Enteric nervous system development: migration, differentiation, and disease. Am. J. Physiol. Gastrointest. Liver Physiol. 305, G1–G24 (2013).

    81. Goldstein, A. M., Hofstra, R. M. & Burns, A. J. Building a brain in the gut: development of the enteric nervous system. Clin. Genet. 83, 307–316 (2013).

    82. Obermayr, F., Hotta, R., Enomoto, H. & Young, H. M. Development and developmental disorders of the enteric nervous system. Nat. Rev. Gastroenterol. Hepatol. 10, 43–57 (2012).

    必看

    Hirschsprung disease, associated syndromes and genetics: a review

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  • 原文地址:https://www.cnblogs.com/leezx/p/10826150.html
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